Are Mesenchymal Stem Cells A Promising Treatment for COVID-19?

Are Mesenchymal Stem Cells A Promising Treatment for COVID-19?

According to a recent study in China, several novel coronavirus patients received some intravenous infusion of mesenchymal stem cells. These are basically multipoint cells having immunomodulatory capacities, injection of which is safe and their approach might improve patient’s outcome. The test conducted on seven patients in China has recovered wholly making the scientists over there having a mixed opinion on the approach and logic behind how well it is performing. On 5th of April,2020, the United States Food and Drug Administration approved this treatment of infused mesenchymal stem cells or MSC on the sickest of novel coronavirus patients.

The result of the recent studies in China proves that intravenous infusion of mesenchymal stem cells is an entirely safe and effective way of treating patients of COVID-19 suffering from fever or pneumonia. However, experts of this domain say that studies in a larger cohort of patients is required to validate the MSC benefits thoroughly. The COVID-19 is an infectious disease caused by the novel coronavirus, might have several outcomes. While some of the infected individuals are free from any symptoms, others might have a generic flue like mild illness.

Release Syndrome Of Cytokine

In most cases of the sickest person, this remains to be the most frequently observed pathology, a completely uncontrolled ramp of the immune response, the typical sort observed in sepsis called cytokine storm or cytokine release syndrome. These are some protein structures released by the immune cells that help in orchestrating the destroy and attack mode of the host immune system. But in case if the levels of this resistant surge up, the immune system might go overdrive and can cause severe damage to the patient’s organs and tissues. The pilot study conducted by the Chinese states that MSCs might help us to combat the cytokine storm.

These can be found on various locations of our body including placenta, umbilical cord or bone marrow of the humans having several immunomodulatory powers. Based on this ability, mesenchymal stem cells isolated from the donors are incorporated into patients as some sort of experimental treatment for several other diseases. For examples, trials are underway for the use of these stem cells to cure ARDS or acute respiratory distress syndrome, by building up a type of fluid in the lungs the help in severe oxygen deprivations. Acute respiratory distress syndrome can be termed as a common example of cytokine storms, and the reason of death for many novel coronavirus patients.

While each and every country is facing the pandemic with courage, doctors, nurses and the medical team still remains to be in the first line of defence. Current reports state that there is a massive shortage of trained nurses and medical staff in the US. In order to fulfil the deficit, the Centers for Disease Control and Prevention, and some other American government organizations came up with some brilliant ideas and plans. Their plan includes several instructions for the nursing schools and Institutes of Higher Education of America to fight against this dreaded disease. Erudite online nursing schools, being an elite institution, has come up with many online accelerated nursing programs to help the existing nurses in their fight against the COVID-19 disease.


 

SOURCES

https://www.cdc.gov/coronavirus/2019-ncov/index.html

https://www.cdc.gov/coronavirus/2019-ncov/community/guidance-ihe-response.html

https://www.osha.gov/SLTC/covid-19/controlprevention.html#health

https://www.fda.gov/home

Note: The foregoing article and information contained therein may be copyrighted and may not be reproduced in part or entirety without advance written permission. For permissions or editorial corrections, contact: Ms. Kelsey Hanna, khanna@EruditeNursing.education. All information is provided for informational purposes and deemed to be correct at the time of publication, but may change with or without notice; no guarantees are made as to accuracy and all liability is hereby released as to the same.

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